Measurement of blood lactate levels and excess lactate as indices of hypoxia during anaesthesia

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Observations of blood lactate and pyruvate levels and excess lactate production during and after anaesthesia with and without hyperventilation.

Arterial blood levels of lactate and pyruvate and the production of excess lactate were studied in two groups of patients. One group of ten patients was anaesthetized with < 1 per cent halothane, nitrous oxide and oxygen and allowed to breathe spontaneously. The second group of twelve patients was anaesthetized with nitrous oxide and oxygen, and additional trichloroethylene or papaveretum, and ...

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Prediction of Respiratory Morbidities in Late Preterm Neonates Using Cord Blood Arterial Lactate and Base Excess

Background: Late preterm neonates may have the external appearance and behavior similar to their counterparts.However, they are susceptible to various neonatal morbidities , due to their physiological and metabolical immaturity.To assess the correlation between cord blood arterial lactate levels and base excess with the development ofrespiratory distress in late preterm neonat...

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Lactate measurement: arterial versus capillary blood

Lactate is the end product of the metabolic process of glucose utilization, known as anaerobic glycolysis, which occurs in the cytosol of all cells. In well-oxygenated tissues this lactate is metabolized further, but if tissues are inadequately oxygenated, lactate accumulates locally and blood concentration rises. As a sensitive but non-specific blood marker of tissue hypoxia, point-ofcare (POC...

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Lactate measurement: arterial versus venous blood sampling

Lactate is the end product of the metabolic process of glucose utilization, known as anaerobic glycolysis, which occurs in the cytoplasm of all cells. In well-oxygenated tissues this lactate is metabolized further, but if tissues are inadequately oxygenated, lactate accumulates locally and blood concentration increases. As a blood marker of tissue hypoxia, lactate measurement has long-establish...

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Accuracy of a hand-held lactate meter in measuring umbilical cord blood lactate at all lactate levels

Objective: Fetal scalp lactate has largely replaced pH analysis to assess intrapartum hypoxia. Many obstetrics units use hand-held lactate meters to measure umbilical blood because of its affordability and ease of use. We sought to investigate the agreement of Lactate Pro with a reference method blood gas analyser and to determine its usefulness with a recommended cutoff value of 4.8 mmol/L. Me...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 1968

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.1968.tb00115.x